NY Daily News reports:
In an upcoming ABC interview with Barbara Walters, Winfrey flat out states, “I’m not a lesbian.”

“I’m not even kind of a lesbian,” the talk show queen, 56, tells Walters. “And the reason why [the rumor] irritates me is because it means that somebody must think I’m lying. That’s No. 1. No. 2 … why would you want to hide it? That is not the way I run my life.”